It acts quickly and is reversed quickly. Signs and symptoms of toxicity possibly being that of altered blood ph and mental status changes.
Nipride is a potent vasodilator but must be protected from light.
Signs of cyanide toxicity from nipride. Nipride sodium nitroprusside is indicated for hypertensive crisis acute pulmonary edema and congestive heart failure. It decreases cardiac afterload. Nipride is a potent vasodilator but must be protected from light.
It acts quickly and is reversed quickly. Nipride is cyanide toxic. Signs and symptoms of toxicity possibly being that of altered blood ph and mental status changes.
National EMS Education Standard Competencies. Autonomic pharmacology pp 649-653 Metabolism and excretion pp 646-647 Mechanism of action pp 626-631 Phases of medication activity pp 646-647 Medication response relationships pp 630-631 635-639 Medication interactions pp 639-640 Toxicity pp 628 636-638 National EMS Education Standard Competencies. Sodium nitroprusside requires not only careful hemodynamic monitoring often necessitating indwelling catheters but also monitoring for cyanide toxicity especially in the presence of renal dysfunction.
Sodium nitroprusside should be titrated to off rather than abruptly stopped because of the potential for rebound hypertension.